Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells

Asymmetric cell division can generate daughter cells with cell size asymmetry, but the underlying mechanisms are not clear. Here the authors show that spatiotemporally controlled Myosin flows together with spindle asymmetry and positioning control cleavage furrow position and cortical expansion to e...

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Autores principales: Chantal Roubinet, Anna Tsankova, Tri Thanh Pham, Arnaud Monnard, Emmanuel Caussinus, Markus Affolter, Clemens Cabernard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7b18a155ba4b4dfba64f09be10ab9b97
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