Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells

Asymmetric cell division can generate daughter cells with cell size asymmetry, but the underlying mechanisms are not clear. Here the authors show that spatiotemporally controlled Myosin flows together with spindle asymmetry and positioning control cleavage furrow position and cortical expansion to e...

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Autores principales:	Chantal Roubinet, Anna Tsankova, Tri Thanh Pham, Arnaud Monnard, Emmanuel Caussinus, Markus Affolter, Clemens Cabernard
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7b18a155ba4b4dfba64f09be10ab9b97
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spelling	oai:doaj.org-article:7b18a155ba4b4dfba64f09be10ab9b972021-12-02T14:42:45ZSpatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells10.1038/s41467-017-01391-w2041-1723https://doaj.org/article/7b18a155ba4b4dfba64f09be10ab9b972017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01391-whttps://doaj.org/toc/2041-1723Asymmetric cell division can generate daughter cells with cell size asymmetry, but the underlying mechanisms are not clear. Here the authors show that spatiotemporally controlled Myosin flows together with spindle asymmetry and positioning control cleavage furrow position and cortical expansion to establish physical asymmetry.Chantal RoubinetAnna TsankovaTri Thanh PhamArnaud MonnardEmmanuel CaussinusMarkus AffolterClemens CabernardNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Chantal Roubinet Anna Tsankova Tri Thanh Pham Arnaud Monnard Emmanuel Caussinus Markus Affolter Clemens Cabernard Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells
description	Asymmetric cell division can generate daughter cells with cell size asymmetry, but the underlying mechanisms are not clear. Here the authors show that spatiotemporally controlled Myosin flows together with spindle asymmetry and positioning control cleavage furrow position and cortical expansion to establish physical asymmetry.
format	article
author	Chantal Roubinet Anna Tsankova Tri Thanh Pham Arnaud Monnard Emmanuel Caussinus Markus Affolter Clemens Cabernard
author_facet	Chantal Roubinet Anna Tsankova Tri Thanh Pham Arnaud Monnard Emmanuel Caussinus Markus Affolter Clemens Cabernard
author_sort	Chantal Roubinet
title	Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells
title_short	Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells
title_full	Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells
title_fullStr	Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells
title_full_unstemmed	Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells
title_sort	spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7b18a155ba4b4dfba64f09be10ab9b97
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Spatio-temporally separated cortical flows and spindle geometry establish physical asymmetry in fly neural stem cells

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