Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair

Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair

Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.

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Auteurs principaux: Hiroyuki Niida, Ryoichi Matsunuma, Ryo Horiguchi, Chiharu Uchida, Yuka Nakazawa, Akira Motegi, Koji Nishimoto, Satoshi Sakai, Tatsuya Ohhata, Kyoko Kitagawa, Shinichi Moriwaki, Hideo Nishitani, Ayako Ui, Tomoo Ogi, Masatoshi Kitagawa
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Science
Q
Accès en ligne:https://doaj.org/article/7b24a512b5c14b5d8915f3a1439eca2b
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Résumé:Repair of cyclobutane pyrimidine dimers requires access to DNA by the nucleotide excision repair machinery. Here the authors show that HBO1 facilitates accumulation of SNF2H and ACF1 to make chromatin more accessible after ultraviolet damage.

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