G-395A polymorphism in the promoter region of the KLOTHO gene associates with frailty among the oldest-old

Abstract Frailty is characterized by a decline in physiological reserve and increased vulnerability. Previous studies have shown that KLOTHO (KL) plays a protective role in several age-related diseases. We hypothesize a probable protective effect of KL on frailty in the elderly population and includ...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Qiukui Hao, Yuting Wang, Xiang Ding, Biao Dong, Ming Yang, Birong Dong, Yuquan Wei
Format: article
Langue:EN
Publié: Nature Portfolio 2018
Sujets:
R
Q
Accès en ligne:https://doaj.org/article/7b283425b40a43b4b26be68133de5933
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!