Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in <italic toggle="yes">Bacillus anthracis</italic>

Analysis of Whole-Genome Sequences for the Prediction of Penicillin Resistance and β-Lactamase Activity in <italic toggle="yes">Bacillus anthracis</italic>

ABSTRACT Penicillin (PEN) is a low-cost option for anthrax treatment, but naturally occurring resistance has been reported. β-Lactamase expression (bla1, bla2) in Bacillus anthracis is regulated by a sigma factor (SigP) and its cognate anti-sigma factor (RsiP). Mutations leading to truncation of Rsi...

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Bibliographic Details
Main Authors: A. S. Gargis, H. P. McLaughlin, A. B. Conley, C. Lascols, P. A. Michel, J. E. Gee, C. K. Marston, C. B. Kolton, L. M. Rodriguez-R, A. R. Hoffmaster, L. M. Weigel, D. Sue
Format: article
Language:EN
Published: American Society for Microbiology 2018
Subjects:
Bacillus anthracis
anthrax
penicillin resistance
whole-genome sequencing
Microbiology
QR1-502
Online Access:https://doaj.org/article/7b451bcdb22f4bc8935dfc67e2310a63
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https://doaj.org/article/7b451bcdb22f4bc8935dfc67e2310a63

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