Nanoscale spatial dependence of avidity in an IgG1 antibody

Abstract Antibodies are secreted proteins that are crucial to recognition of pathogens by the immune system and are also efficient pharmaceuticals. The affinity and specificity of target recognition can increase remarkably through avidity effects, when the antibody can bind a multivalent antigen thr...

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Autores principales: Agnieszka Jendroszek, Magnus Kjaergaard
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7b8a3aa37c394da7b6321624c51f9191
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