Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply

Lipoprotein lipase regulates hematopoietic stem progenitor cell maintenance through DHA supply

Lipoprotein lipase (LPL) hydrolyzes triglycerides to supply free fatty acids (FFAs) to muscle for energy and adipocytes for storage. Here, the authors demonstrate that Lpl and its product, the FFA docosahexaenoic acid (DHA) are required for haematopoietic stem progenitor cell expansion during zebraf...

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Bibliographic Details
Main Authors: Chao Liu, Tianxu Han, David L. Stachura, Huawei Wang, Boris L. Vaisman, Jungsu Kim, Richard L. Klemke, Alan T. Remaley, Tariq M. Rana, David Traver, Yury I. Miller
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Science
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Online Access:https://doaj.org/article/7b8b171e2a974a31aa37f80a6f9e12b7
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