siRNA-loaded poly(histidine-arginine)6-modified chitosan nanoparticle with enhanced cell-penetrating and endosomal escape capacities for suppressing breast tumor metastasis

siRNA-loaded poly(histidine-arginine)6-modified chitosan nanoparticle with enhanced cell-penetrating and endosomal escape capacities for suppressing breast tumor metastasis

Ping Sun,1 Wei Huang,1 Lin Kang,1 Mingji Jin,1 Bo Fan,1 Hongyan Jin,2 Qi-Ming Wang,1 Zhonggao Gao1 1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Department of Pharmaceutics, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical C...

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Autores principales: Sun P, Huang W, Kang L, Jin M, Fan B, Jin H, Wang Q, Gao Z
Formato: article
Lenguaje:EN
Publicado: Dove Medical Press 2017
Materias:
Poly(histidine-arginine)6 peptide modified chitosan nanoparticle
Cell penetrating peptides
Endosome/lysosome escape
Gene delivery
Breast carcinoma Abbreviations
Medicine (General)
R5-920
Acceso en línea:https://doaj.org/article/7b95d9a0a1414f7d9cd67ea76cd89462
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https://doaj.org/article/7b95d9a0a1414f7d9cd67ea76cd89462

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