Mitochondrial calcium uniporter is essential for hearing and hair cell preservation in congenic FVB/NJ mice

Abstract Mitochondrial Ca2+ regulates a wide range of cell processes, including morphogenesis, metabolism, excitotoxicity, and survival. In cochlear hair cells, the activation of mechano-electrical transduction and voltage-gated Ca2+ channels result in a large influx of Ca2+. The intracellular rise...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Mayakannan Manikandan, Steven Walker, Aditi R. Deshmukh, Elizabeth Perea, Danqi Wang, Kumar N. Alagramam, Ruben Stepanyan
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
R
Q
Acceso en línea:https://doaj.org/article/7b994349ac5141cc975fc7bdd5f3f50d
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!