Mitochondrial calcium uniporter is essential for hearing and hair cell preservation in congenic FVB/NJ mice
Abstract Mitochondrial Ca2+ regulates a wide range of cell processes, including morphogenesis, metabolism, excitotoxicity, and survival. In cochlear hair cells, the activation of mechano-electrical transduction and voltage-gated Ca2+ channels result in a large influx of Ca2+. The intracellular rise...
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Autores principales: | Mayakannan Manikandan, Steven Walker, Aditi R. Deshmukh, Elizabeth Perea, Danqi Wang, Kumar N. Alagramam, Ruben Stepanyan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/7b994349ac5141cc975fc7bdd5f3f50d |
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