Validation of ultrasound bioimaging to predict worm burden and treatment efficacy in preclinical filariasis drug screening models

Abstract Filariasis is a global health problem targeted for elimination. Curative drugs (macrofilaricides) are required to accelerate elimination. Candidate macrofilaricides require testing in preclinical models of filariasis. The incidence of infection failures and high intra-group variation means...

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Autores principales: Amy E. Marriott, Hanna Sjoberg, Hayley Tyrer, Joanne Gamble, Emma Murphy, John Archer, Andrew Steven, Mark J. Taylor, Joseph D. Turner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/7bc2b8d4bdf1456b87027d72ef7bff3e
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