Teleost fish mount complex clonal IgM and IgT responses in spleen upon systemic viral infection.

Upon infection, B-lymphocytes expressing antibodies specific for the intruding pathogen develop clonal responses triggered by pathogen recognition via the B-cell receptor. The constant region of antibodies produced by such responding clones dictates their functional properties. In teleost fish, the...

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Autores principales: Rosario Castro, Luc Jouneau, Hang-Phuong Pham, Olivier Bouchez, Véronique Giudicelli, Marie-Paule Lefranc, Edwige Quillet, Abdenour Benmansour, Frédéric Cazals, Adrien Six, Simon Fillatreau, Oriol Sunyer, Pierre Boudinot
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/7be38ef00475454db7f8e1a913d761bf
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