The genotypic false positive rate determined by V3 population sequencing can predict the burden of HIV-1 CXCR4-using species detected by pyrosequencing.

The genotypic false positive rate determined by V3 population sequencing can predict the burden of HIV-1 CXCR4-using species detected by pyrosequencing.

<h4>Objective</h4>The false-positive rate (FPR) is a percentage-score provided by Geno2Pheno-algorithm indicating the likelihood that a V3-sequence is falsely predicted as CXCR4-using. We evaluated the correlation between FPR obtained by V3 population-sequencing and the burden of CXCR4-u...

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Main Authors: Valentina Svicher, Valeria Cento, Gabriella Rozera, Isabella Abbate, Maria Mercedes Santoro, Daniele Armenia, Lavinia Fabeni, Alessandro Bruselles, Alessandra Latini, Guido Palamara, Valeria Micheli, Giuliano Rizzardini, Caterina Gori, Federica Forbici, Giuseppe Ippolito, Massimo Andreoni, Andrea Antinori, Francesca Ceccherini-Silberstein, Maria Rosaria Capobianchi, Carlo Federico Perno
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/7be4060c35a74e85964f9b67de9f8f00
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https://doaj.org/article/7be4060c35a74e85964f9b67de9f8f00

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