Nitric oxide-sensitive guanylyl cyclase is differentially regulated by nuclear and non-nuclear estrogen pathways in anterior pituitary gland.

17β-estradiol (E2) regulates hormonal release as well as proliferation and cell death in the pituitary. The main nitric oxide receptor, nitric oxide sensitive- or soluble guanylyl cyclase (sGC), is a heterodimer composed of two subunits, α and β, that catalyses cGMP formation. α1β1 is the most abund...

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Autores principales: Jimena P Cabilla, Silvana I Nudler, Sonia A Ronchetti, Fernanda A Quinteros, Mercedes Lasaga, Beatriz H Duvilanski
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2011
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Acceso en línea:https://doaj.org/article/7be74572b80e4608ace524d88e2e09fd
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