Evolutionary dynamics and genomic features of the Elizabethkingia anophelis 2015 to 2016 Wisconsin outbreak strain

Evolutionary dynamics and genomic features of the Elizabethkingia anophelis 2015 to 2016 Wisconsin outbreak strain

Elizabethkingia anophelis is an emerging pathogen of high antimicrobial resistance. Perrin and colleagues sequenced isolates of a 2015/2016 E. anophelis outbreak in Wisconsin and found substantial genetic diversity, accelerated evolutionary rate and a disruptive mutation in the DNA repair gene mutY.

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Auteurs principaux: Amandine Perrin, Elise Larsonneur, Ainsley C. Nicholson, David J. Edwards, Kristin M. Gundlach, Anne M. Whitney, Christopher A. Gulvik, Melissa E. Bell, Olaya Rendueles, Jean Cury, Perrine Hugon, Dominique Clermont, Vincent Enouf, Vladimir Loparev, Phalasy Juieng, Timothy Monson, David Warshauer, Lina I. Elbadawi, Maroya Spalding Walters, Matthew B. Crist, Judith Noble-Wang, Gwen Borlaug, Eduardo P. C. Rocha, Alexis Criscuolo, Marie Touchon, Jeffrey P. Davis, Kathryn E. Holt, John R. McQuiston, Sylvain Brisse
Format: article
Langue:EN
Publié: Nature Portfolio 2017
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Science
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Accès en ligne:https://doaj.org/article/7bec1d98c42045e89f4d0f4a501bc3d9
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Résumé:Elizabethkingia anophelis is an emerging pathogen of high antimicrobial resistance. Perrin and colleagues sequenced isolates of a 2015/2016 E. anophelis outbreak in Wisconsin and found substantial genetic diversity, accelerated evolutionary rate and a disruptive mutation in the DNA repair gene mutY.

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