Dihydrofolate Reductase Is a Valid Target for Antifungal Development in the Human Pathogen <italic toggle="yes">Candida albicans</italic>
ABSTRACT While the folate biosynthetic pathway has provided a rich source of antibacterial, antiprotozoal, and anticancer therapies, it has not yet been exploited to develop uniquely antifungal agents. Although there have been attempts to develop fungal-specific inhibitors of dihydrofolate reductase...
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Format: | article |
Langue: | EN |
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American Society for Microbiology
2020
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Accès en ligne: | https://doaj.org/article/7bedfb15049f4488a03cf31477b69091 |
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