Dihydrofolate Reductase Is a Valid Target for Antifungal Development in the Human Pathogen <italic toggle="yes">Candida albicans</italic>

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Dihydrofolate Reductase Is a Valid Target for Antifungal Development in the Human Pathogen <italic toggle="yes">Candida albicans</italic>

ABSTRACT While the folate biosynthetic pathway has provided a rich source of antibacterial, antiprotozoal, and anticancer therapies, it has not yet been exploited to develop uniquely antifungal agents. Although there have been attempts to develop fungal-specific inhibitors of dihydrofolate reductase...

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Autores principales:	Christian DeJarnette, Arturo Luna-Tapia, Leanna R. Estredge, Glen E. Palmer
Formato:	article
Lenguaje:	EN
Publicado:	American Society for Microbiology 2020
Materias:	Candida albicans antifungal agents dihydrofolate reductase Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/7bedfb15049f4488a03cf31477b69091
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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