The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin

The Structural Basis for a Transition State That Regulates Pore Formation in a Bacterial Toxin

ABSTRACT The cholesterol-dependent cytolysin (CDC) genes are present in bacterial species that span terrestrial, vertebrate, and invertebrate niches, which suggests that they have evolved to function under widely different environmental conditions. Using a combination of biophysical and crystallogra...

Full description

Saved in:
Bibliographic Details
Main Authors: Kristin R. Wade, Sara L. Lawrence, Allison J. Farrand, Eileen M. Hotze, Michael J. Kuiper, Michael A. Gorman, Michelle P. Christie, Santosh Panjikar, Craig J. Morton, Michael W. Parker, Rodney K. Tweten
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
cold denaturation
complement
gasdermin
perforin
water network
Microbiology
QR1-502
Online Access:https://doaj.org/article/7bf35b5ddc6847bfb07b9a7eda692855
Tags: Add Tag
No Tags, Be the first to tag this record!
Be the first to leave a comment!
You must be logged in first

Similar Items