Identification and Characterization of a Novel Epitope of ASFV-Encoded dUTPase by Monoclonal Antibodies

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Identification and Characterization of a Novel Epitope of ASFV-Encoded dUTPase by Monoclonal Antibodies

Deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase) of African swine fever virus (ASFV) is an essential enzyme required for efficient virus replication. Previous crystallography data have indicated that dUTPase (E165R) may serve as a therapeutic target for inhibiting ASFV replication; however...

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Main Authors:	Shuai Zhang, Rui Wang, Xiaojing Zhu, Jiaxin Jin, Wenlong Lu, Xuyang Zhao, Bo Wan, Yifei Liao, Qin Zhao, Christopher L. Netherton, Guoqing Zhuang, Aijun Sun, Gaiping Zhang
Format:	article
Language:	EN
Published:	MDPI AG 2021
Subjects:	African swine fever virus African swine fever dUTPase epitope therapeutic drug Microbiology QR1-502
Online Access:	https://doaj.org/article/7bf9166b19c249e1966f43b0568de2ef
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