Trib1 deficiency causes brown adipose respiratory chain depletion and mitochondrial disorder

Abstract Tribbles homolog 1 (TRIB1) belongs to the Tribbles family of pseudokinases, which plays a key role in tumorigenesis and inflammation. Although genome-wide analysis shows that TRIB1 expression is highly correlated with blood lipid levels, the relationship between TRIB1 and adipose tissue met...

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Auteurs principaux: Xuelian Zhang, Bin Zhang, Chenyang Zhang, Guibo Sun, Xiaobo Sun
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
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Accès en ligne:https://doaj.org/article/7c3a574735e44118a747b838ecc600d8
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