Mbnl1 and Mbnl2 regulate brain structural integrity in mice

Sta Maria et al. use 2D MRI to study brains from mice deficient in Mbnl1 and/or Mbnl2 as these Muscleblind-like proteins are thought to play a role in Myotonic Dystrophy Type I (DM1). They show brain region-specific reductions in white and gray matter that could help to explain the variability in th...

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Autores principales: Naomi S. Sta Maria, Chenyu Zhou, Se Jung Lee, Parvin Valiulahi, Xiandu Li, Jongkyu Choi, Xiaodan Liu, Russell Jacobs, Lucio Comai, Sita Reddy
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/7c59e0e8b3664c738c7862241cad5694
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