Mbnl1 and Mbnl2 regulate brain structural integrity in mice

Sta Maria et al. use 2D MRI to study brains from mice deficient in Mbnl1 and/or Mbnl2 as these Muscleblind-like proteins are thought to play a role in Myotonic Dystrophy Type I (DM1). They show brain region-specific reductions in white and gray matter that could help to explain the variability in th...

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Autores principales:	Naomi S. Sta Maria, Chenyu Zhou, Se Jung Lee, Parvin Valiulahi, Xiandu Li, Jongkyu Choi, Xiaodan Liu, Russell Jacobs, Lucio Comai, Sita Reddy
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/7c59e0e8b3664c738c7862241cad5694
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

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spelling	oai:doaj.org-article:7c59e0e8b3664c738c7862241cad56942021-12-05T12:08:07ZMbnl1 and Mbnl2 regulate brain structural integrity in mice10.1038/s42003-021-02845-02399-3642https://doaj.org/article/7c59e0e8b3664c738c7862241cad56942021-11-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-02845-0https://doaj.org/toc/2399-3642Sta Maria et al. use 2D MRI to study brains from mice deficient in Mbnl1 and/or Mbnl2 as these Muscleblind-like proteins are thought to play a role in Myotonic Dystrophy Type I (DM1). They show brain region-specific reductions in white and gray matter that could help to explain the variability in the brain structural alterations reported in DM1.Naomi S. Sta MariaChenyu ZhouSe Jung LeeParvin ValiulahiXiandu LiJongkyu ChoiXiaodan LiuRussell JacobsLucio ComaiSita ReddyNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Naomi S. Sta Maria Chenyu Zhou Se Jung Lee Parvin Valiulahi Xiandu Li Jongkyu Choi Xiaodan Liu Russell Jacobs Lucio Comai Sita Reddy Mbnl1 and Mbnl2 regulate brain structural integrity in mice
description	Sta Maria et al. use 2D MRI to study brains from mice deficient in Mbnl1 and/or Mbnl2 as these Muscleblind-like proteins are thought to play a role in Myotonic Dystrophy Type I (DM1). They show brain region-specific reductions in white and gray matter that could help to explain the variability in the brain structural alterations reported in DM1.
format	article
author	Naomi S. Sta Maria Chenyu Zhou Se Jung Lee Parvin Valiulahi Xiandu Li Jongkyu Choi Xiaodan Liu Russell Jacobs Lucio Comai Sita Reddy
author_facet	Naomi S. Sta Maria Chenyu Zhou Se Jung Lee Parvin Valiulahi Xiandu Li Jongkyu Choi Xiaodan Liu Russell Jacobs Lucio Comai Sita Reddy
author_sort	Naomi S. Sta Maria
title	Mbnl1 and Mbnl2 regulate brain structural integrity in mice
title_short	Mbnl1 and Mbnl2 regulate brain structural integrity in mice
title_full	Mbnl1 and Mbnl2 regulate brain structural integrity in mice
title_fullStr	Mbnl1 and Mbnl2 regulate brain structural integrity in mice
title_full_unstemmed	Mbnl1 and Mbnl2 regulate brain structural integrity in mice
title_sort	mbnl1 and mbnl2 regulate brain structural integrity in mice
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/7c59e0e8b3664c738c7862241cad5694
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Mbnl1 and Mbnl2 regulate brain structural integrity in mice

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