Capicua regulates neural stem cell proliferation and lineage specification through control of Ets factors

Although Capicua (Cic), a transcriptional repressor, is linked to cancer, little is known about its function in the non-diseased brain. Here, authors show that Cic is strongly expressed in astrocytic and neuronal lineage cells during development and regulates proliferation and lineage selection via...

Full description

Saved in:
Bibliographic Details
Main Authors: Shiekh Tanveer Ahmad, Alexandra D. Rogers, Myra J. Chen, Rajiv Dixit, Lata Adnani, Luke S. Frankiw, Samuel O. Lawn, Michael D. Blough, Mana Alshehri, Wei Wu, Marco A. Marra, Stephen M. Robbins, J. Gregory Cairncross, Carol Schuurmans, Jennifer A. Chan
Format: article
Language:EN
Published: Nature Portfolio 2019
Subjects:
Q
Online Access:https://doaj.org/article/7c701ae587344f44b0639d92de89cde9
Tags: Add Tag
No Tags, Be the first to tag this record!