Enhanced immune response and protective effects of nano-chitosan-based DNA vaccine encoding T cell epitopes of Esat-6 and FL against Mycobacterium tuberculosis infection.

Development of a novel and effective vaccine against Mycobacterium tuberculosis (M.tb) is a challenging for preventing TB infection. In this study, a novel nanoparticle-based recombinant DNA vaccine was developed, which contains Esat-6 three T cell epitopes (Esat-6/3e) and fms-like tyrosine kinase 3...

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Autores principales: Ganzhu Feng, Qingtao Jiang, Mei Xia, Yanlai Lu, Wen Qiu, Dan Zhao, Liwei Lu, Guangyong Peng, Yingwei Wang
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/7ce456d299fa4b4b879e143fbb5ab12a
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