Enhanced immune response and protective effects of nano-chitosan-based DNA vaccine encoding T cell epitopes of Esat-6 and FL against Mycobacterium tuberculosis infection.

Development of a novel and effective vaccine against Mycobacterium tuberculosis (M.tb) is a challenging for preventing TB infection. In this study, a novel nanoparticle-based recombinant DNA vaccine was developed, which contains Esat-6 three T cell epitopes (Esat-6/3e) and fms-like tyrosine kinase 3...

Full description

Saved in:
Bibliographic Details
Main Authors: Ganzhu Feng, Qingtao Jiang, Mei Xia, Yanlai Lu, Wen Qiu, Dan Zhao, Liwei Lu, Guangyong Peng, Yingwei Wang
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
R
Q
Online Access:https://doaj.org/article/7ce456d299fa4b4b879e143fbb5ab12a
Tags: Add Tag
No Tags, Be the first to tag this record!