HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes.

<h4>Background</h4>We previously demonstrated the small heat shock protein, HSPB1, to prevent tachycardia remodeling in in vitro and in vivo models for Atrial Fibrillation (AF). To gain insight into its mechanism of action, we examined the protective effect of all 10 members of the HSPB...

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Main Authors: Lei Ke, Roelien A M Meijering, Femke Hoogstra-Berends, Katarina Mackovicova, Michel J Vos, Isabelle C Van Gelder, Robert H Henning, Harm H Kampinga, Bianca J J M Brundel
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
R
Q
Online Access:https://doaj.org/article/7ceac7bc851f4a02b6f29f6b85772222
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