De novo histidine biosynthesis protects Mycobacterium tuberculosis from host IFN-γ mediated histidine starvation
Dwivedy and Ashraf et al. use a hisD knockout strain of M. tuberculosis to show that the mouse immune system controls and eliminates the hisD knockout strain by inducing an IFNγ-dependent depletion of host histidine. These results suggest a link between histidine metabolism and the pathogenesis of M...
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| Main Authors: | , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Nature Portfolio
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/7d47e0c235c843a1813bce3b53c64a6f |
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