The TCL1A oncoprotein interacts directly with the NF-kappaB inhibitor IkappaB.
The T cell leukaemia/lymphoma 1A (TCL1A) oncoprotein plays key roles in several B and T cell malignancies. Lacking enzymatic activity, TCL1A's transforming action was linked to its capacity to co-activate the protein kinase AKT via binding to its pleckstrin homology (PH) domain. However, pertur...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | article |
| Language: | EN |
| Published: |
Public Library of Science (PLoS)
2009
|
| Subjects: | |
| Online Access: | https://doaj.org/article/7d4b5717a52e4914b5b4b05fba8d09ec |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Be the first to leave a comment!