Identification and activation of TLR4-mediated signalling pathways by alginate-derived guluronate oligosaccharide in RAW264.7 macrophages

Abstract Alginate, a natural acidic polysaccharide extracted from marine brown seaweeds, is composed of different blocks of β-(1, 4)-D-mannuronate (M) and its C-5 epimer α-(1, 4)-L-guluronate (G). Alginate-derived guluronate oligosaccharide (GOS) readily activates macrophages. However, to understand...

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Bibliographic Details
Main Authors: Weishan Fang, Decheng Bi, Ruijin Zheng, Nan Cai, Hong Xu, Rui Zhou, Jun Lu, Min Wan, Xu Xu
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
R
Q
Online Access:https://doaj.org/article/7d965d16a035441bab4e51b87eefd8ae
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