The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription

BmrR is a member of the bacterial MerR transcription factor family that regulates the expression of the bacterial efflux pump Bmr. Here, the authors present the cryo-EM structure of a B. subtilis transcription activation complex (TAC) containing the RNA Polymerase (RNAP) core enzyme, σA, promoter DN...

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Auteurs principaux: Chengli Fang, Linyu Li, Yihan Zhao, Xiaoxian Wu, Steven J. Philips, Linlin You, Mingkang Zhong, Xiaojin Shi, Thomas V. O’Halloran, Qunyi Li, Yu Zhang
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/7d9919e66d8647f8ae01f45fa7ead1ad
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