Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate
Abstract While cancer cells gain aggressiveness by mutations, abundant mutations release neoantigens, attracting anti-cancer immune cells. We hypothesized that in breast cancer (BC), where mutation is less common, tumors with high mutation rates demonstrate aggressive phenotypes and attract immune c...
Guardado en:
Autores principales: | Hideo Takahashi, Mariko Asaoka, Li Yan, Omar M. Rashid, Masanori Oshi, Takashi Ishikawa, Masayuki Nagahashi, Kazuaki Takabe |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/7da8c6f6d26c4ed3a1ec4b0f1f4f5d48 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
M1 Macrophage and M1/M2 ratio defined by transcriptomic signatures resemble only part of their conventional clinical characteristics in breast cancer
por: Masanori Oshi, et al.
Publicado: (2020) -
Low expression of miR-29a is associated with aggressive biology and worse survival in gastric cancer
por: Yoshihisa Tokumaru, et al.
Publicado: (2021) -
Mitochondrial mutations drive prostate cancer aggression
por: Julia F. Hopkins, et al.
Publicado: (2017) -
Adipogenesis in triple-negative breast cancer is associated with unfavorable tumor immune microenvironment and with worse survival
por: Masanori Oshi, et al.
Publicado: (2021) -
Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer
por: Kristi Krüger, et al.
Publicado: (2017)