Biologically Aggressive Phenotype and Anti-cancer Immunity Counterbalance in Breast Cancer with High Mutation Rate
Abstract While cancer cells gain aggressiveness by mutations, abundant mutations release neoantigens, attracting anti-cancer immune cells. We hypothesized that in breast cancer (BC), where mutation is less common, tumors with high mutation rates demonstrate aggressive phenotypes and attract immune c...
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Main Authors: | Hideo Takahashi, Mariko Asaoka, Li Yan, Omar M. Rashid, Masanori Oshi, Takashi Ishikawa, Masayuki Nagahashi, Kazuaki Takabe |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2020
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Online Access: | https://doaj.org/article/7da8c6f6d26c4ed3a1ec4b0f1f4f5d48 |
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