Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease

Yap regulates skeletal muscle fatty acid oxidation and adiposity in metabolic disease

The mechanisms driving metabolic dysfunction in obesity remain incompletely understood. Here, the authors show that the levels of Hippo pathway effector YAP are reduced in muscle from individuals with insulin resistance and obese-diabetic mice, and that YAP promotes skeletal muscle lipid metabolism...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: K. I. Watt, D. C. Henstridge, M. Ziemann, C. B. Sim, M. K. Montgomery, D. Samocha-Bonet, B. L. Parker, G. T. Dodd, S. T. Bond, T. M. Salmi, R. S. Lee, R. E. Thomson, A. Hagg, J. R. Davey, H. Qian, R. Koopman, A. El-Osta, J. R. Greenfield, M. J. Watt, M. A. Febbraio, B. G. Drew, A. G. Cox, E. R. Porrello, K. F. Harvey, P. Gregorevic
Format: article
Langue:EN
Publié: Nature Portfolio 2021
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/7dcbc3af56b043379fc3d456b0978176
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Internet

https://doaj.org/article/7dcbc3af56b043379fc3d456b0978176

Documents similaires