Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring

The molecular mechanisms that restrict synapse formation with incorrect partners remain unclear. Here, authors use 4D imaging in developing Drosophila brains to show that filopodial kinetics are regulated by autophagy and this restricts inappropriate partner choice through a process of kinetic exclu...

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Auteurs principaux: Ferdi Ridvan Kiral, Gerit Arne Linneweber, Thomas Mathejczyk, Svilen Veselinov Georgiev, Mathias F. Wernet, Bassem A. Hassan, Max von Kleist, Peter Robin Hiesinger
Format: article
Langue:EN
Publié: Nature Portfolio 2020
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Accès en ligne:https://doaj.org/article/7dd26b1025524b628b2b4f76849c0554
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