Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring

The molecular mechanisms that restrict synapse formation with incorrect partners remain unclear. Here, authors use 4D imaging in developing Drosophila brains to show that filopodial kinetics are regulated by autophagy and this restricts inappropriate partner choice through a process of kinetic exclu...

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Autores principales:	Ferdi Ridvan Kiral, Gerit Arne Linneweber, Thomas Mathejczyk, Svilen Veselinov Georgiev, Mathias F. Wernet, Bassem A. Hassan, Max von Kleist, Peter Robin Hiesinger
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7dd26b1025524b628b2b4f76849c0554
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id	oai:doaj.org-article:7dd26b1025524b628b2b4f76849c0554
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spelling	oai:doaj.org-article:7dd26b1025524b628b2b4f76849c05542021-12-02T14:41:24ZAutophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring10.1038/s41467-020-14781-42041-1723https://doaj.org/article/7dd26b1025524b628b2b4f76849c05542020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14781-4https://doaj.org/toc/2041-1723The molecular mechanisms that restrict synapse formation with incorrect partners remain unclear. Here, authors use 4D imaging in developing Drosophila brains to show that filopodial kinetics are regulated by autophagy and this restricts inappropriate partner choice through a process of kinetic exclusionFerdi Ridvan KiralGerit Arne LinneweberThomas MathejczykSvilen Veselinov GeorgievMathias F. WernetBassem A. HassanMax von KleistPeter Robin HiesingerNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ferdi Ridvan Kiral Gerit Arne Linneweber Thomas Mathejczyk Svilen Veselinov Georgiev Mathias F. Wernet Bassem A. Hassan Max von Kleist Peter Robin Hiesinger Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
description	The molecular mechanisms that restrict synapse formation with incorrect partners remain unclear. Here, authors use 4D imaging in developing Drosophila brains to show that filopodial kinetics are regulated by autophagy and this restricts inappropriate partner choice through a process of kinetic exclusion
format	article
author	Ferdi Ridvan Kiral Gerit Arne Linneweber Thomas Mathejczyk Svilen Veselinov Georgiev Mathias F. Wernet Bassem A. Hassan Max von Kleist Peter Robin Hiesinger
author_facet	Ferdi Ridvan Kiral Gerit Arne Linneweber Thomas Mathejczyk Svilen Veselinov Georgiev Mathias F. Wernet Bassem A. Hassan Max von Kleist Peter Robin Hiesinger
author_sort	Ferdi Ridvan Kiral
title	Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
title_short	Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
title_full	Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
title_fullStr	Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
title_full_unstemmed	Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring
title_sort	autophagy-dependent filopodial kinetics restrict synaptic partner choice during drosophila brain wiring
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/7dd26b1025524b628b2b4f76849c0554
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Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring

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