Peptide-oligourea hybrids analogue of GLP-1 with improved action in vivo
The peptide hormone GLP-1 has the potential to be a remedy for diabetes type II, yet is unstable. Here, the authors synthesized α-peptide-oligourea hybrid analogues of GLP-1 some of which showing significantly prolonged activity in vivo.
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Main Authors: | Juliette Fremaux, Claire Venin, Laura Mauran, Robert H. Zimmer, Gilles Guichard, Sébastien R. Goudreau |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2019
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Online Access: | https://doaj.org/article/7e2c09e5f5e9452e9f698d011ed0817b |
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