Resveratrol sequentially induces replication and oxidative stresses to drive p53-CXCR2 mediated cellular senescence in cancer cells
Abstract Resveratrol (RSV) acts either as an antioxidant or a pro-oxidant depending on contexts. RSV-treated cancer cells may experience replication stress that can lead to cellular senescence or apoptosis. While both oxidative and replication stresses may mediate the anti-proliferation effect of RS...
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Auteurs principaux: | Boxuan Li, Dong Hou, Haiyang Guo, Haibin Zhou, Shouji Zhang, Xiuhua Xu, Qiao Liu, Xiyu Zhang, Yongxin Zou, Yaoqin Gong, Changshun Shao |
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Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2017
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Sujets: | |
Accès en ligne: | https://doaj.org/article/7e4425e2a99343beae19df15d3b512c8 |
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