Differential organization of tonic and chronic B cell antigen receptors in the plasma membrane

Signalling of the B cell receptor (BCR) is pivotal for survival and activation of naïve B cells. Here the authors show, using super-resolution microscopy techniques, that BCRs exist primarily as monomers and dimers in resting B cells, and oligomerize only on stimulation, thereby implicating a functi...

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Autores principales: Maria Angela Gomes de Castro, Hanna Wildhagen, Shama Sograte-Idrissi, Christoffer Hitzing, Mascha Binder, Martin Trepel, Niklas Engels, Felipe Opazo
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/7e46cbba11b14a6585cafa271c7104a1
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