Amino acid sites related to the PB2 subunits of IDV affect polymerase activity

Amino acid sites related to the PB2 subunits of IDV affect polymerase activity

Abstract Background In 2011, a new influenza virus, named Influenza D Virus (IDV), was isolated from pigs, and then cattle, presenting influenza-like symptoms. IDV is one of the causative agents of Bovine Respiratory Disease (BRD), which causes high morbidity and mortality in feedlot cattle worldwid...

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Auteurs principaux: Yutian Wang, Weiyang Sun, Zhenfei Wang, Menglin Zhao, Xinghai Zhang, Yunyi Kong, Xuefeng Wang, Na Feng, Tiecheng Wang, Feihu Yan, Yongkun Zhao, Xianzhu Xia, Songtao Yang, Yuwei Gao
Format: article
Langue:EN
Publié: BMC 2021
Sujets:
Influenza D virus
Viral polymerase
PB2 protein
Single-site mutation
Random mutation library
Mini-replicon reporter constructs
Infectious and parasitic diseases
RC109-216
Accès en ligne:https://doaj.org/article/7e6fe9a271234b668b540526405db785
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https://doaj.org/article/7e6fe9a271234b668b540526405db785

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