High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale
High-content imaging (HCI) is a microscopy technique that permits the screening of multiple cells simultaneously in high resolution to detect subtle morphological and phenotypic variation. The power of this methodology is that it can generate large data sets comprised of multiple parameters taken f...
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American Society for Microbiology
2021
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oai:doaj.org-article:7e8b446402e5440bb347bd6797cfcc672021-12-02T15:16:36ZHigh-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale2379-507710.1128/mSystems.00028-21https://doaj.org/article/7e8b446402e5440bb347bd6797cfcc672021-06-01T00:00:00Zhttps://journals.asm.org/doi/10.1128/mSystems.00028-21https://doaj.org/toc/2379-5077 High-content imaging (HCI) is a microscopy technique that permits the screening of multiple cells simultaneously in high resolution to detect subtle morphological and phenotypic variation. The power of this methodology is that it can generate large data sets comprised of multiple parameters taken from individual cells subjected to a range of different conditions.Sushmita SridharSally ForrestBen WarneMailis MaesStephen BakerGordon DouganJosefin Bartholdson ScottAmerican Society for MicrobiologyarticleMicrobiologyQR1-502ENmSystems, Vol 6, Iss 3 (2021) |
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DOAJ |
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DOAJ |
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EN |
topic |
Microbiology QR1-502 |
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Microbiology QR1-502 Sushmita Sridhar Sally Forrest Ben Warne Mailis Maes Stephen Baker Gordon Dougan Josefin Bartholdson Scott High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale |
description |
High-content imaging (HCI) is a microscopy technique that permits the screening of multiple cells simultaneously in high resolution to detect subtle morphological and phenotypic variation. The power of this methodology is that it can generate large data sets comprised of multiple parameters taken from individual cells subjected to a range of different conditions. |
format |
article |
author |
Sushmita Sridhar Sally Forrest Ben Warne Mailis Maes Stephen Baker Gordon Dougan Josefin Bartholdson Scott |
author_facet |
Sushmita Sridhar Sally Forrest Ben Warne Mailis Maes Stephen Baker Gordon Dougan Josefin Bartholdson Scott |
author_sort |
Sushmita Sridhar |
title |
High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale |
title_short |
High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale |
title_full |
High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale |
title_fullStr |
High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale |
title_full_unstemmed |
High-Content Imaging to Phenotype Antimicrobial Effects on Individual Bacteria at Scale |
title_sort |
high-content imaging to phenotype antimicrobial effects on individual bacteria at scale |
publisher |
American Society for Microbiology |
publishDate |
2021 |
url |
https://doaj.org/article/7e8b446402e5440bb347bd6797cfcc67 |
work_keys_str_mv |
AT sushmitasridhar highcontentimagingtophenotypeantimicrobialeffectsonindividualbacteriaatscale AT sallyforrest highcontentimagingtophenotypeantimicrobialeffectsonindividualbacteriaatscale AT benwarne highcontentimagingtophenotypeantimicrobialeffectsonindividualbacteriaatscale AT mailismaes highcontentimagingtophenotypeantimicrobialeffectsonindividualbacteriaatscale AT stephenbaker highcontentimagingtophenotypeantimicrobialeffectsonindividualbacteriaatscale AT gordondougan highcontentimagingtophenotypeantimicrobialeffectsonindividualbacteriaatscale AT josefinbartholdsonscott highcontentimagingtophenotypeantimicrobialeffectsonindividualbacteriaatscale |
_version_ |
1718387455106744320 |