LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

Lipoma preferred partner (LPP) mediates TGFβ-induced breast cancer cell migration and invasion. Here the authors show that LPP is a Src-family kinase substrate that regulates the formation of protrusions of the plasma membrane -called invadopodia- required for breast cancer metastasis.

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Autores principales: Elaine Ngan, Konstantin Stoletov, Harvey W. Smith, Jessica Common, William J. Muller, John D. Lewis, Peter M. Siegel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/7ea97a33e3164d48a89da3953228c9fb
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