LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

Lipoma preferred partner (LPP) mediates TGFβ-induced breast cancer cell migration and invasion. Here the authors show that LPP is a Src-family kinase substrate that regulates the formation of protrusions of the plasma membrane -called invadopodia- required for breast cancer metastasis.

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Autores principales:	Elaine Ngan, Konstantin Stoletov, Harvey W. Smith, Jessica Common, William J. Muller, John D. Lewis, Peter M. Siegel
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7ea97a33e3164d48a89da3953228c9fb
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spelling	oai:doaj.org-article:7ea97a33e3164d48a89da3953228c9fb2021-12-02T17:01:25ZLPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis10.1038/ncomms150592041-1723https://doaj.org/article/7ea97a33e3164d48a89da3953228c9fb2017-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms15059https://doaj.org/toc/2041-1723Lipoma preferred partner (LPP) mediates TGFβ-induced breast cancer cell migration and invasion. Here the authors show that LPP is a Src-family kinase substrate that regulates the formation of protrusions of the plasma membrane -called invadopodia- required for breast cancer metastasis.Elaine NganKonstantin StoletovHarvey W. SmithJessica CommonWilliam J. MullerJohn D. LewisPeter M. SiegelNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Elaine Ngan Konstantin Stoletov Harvey W. Smith Jessica Common William J. Muller John D. Lewis Peter M. Siegel LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
description	Lipoma preferred partner (LPP) mediates TGFβ-induced breast cancer cell migration and invasion. Here the authors show that LPP is a Src-family kinase substrate that regulates the formation of protrusions of the plasma membrane -called invadopodia- required for breast cancer metastasis.
format	article
author	Elaine Ngan Konstantin Stoletov Harvey W. Smith Jessica Common William J. Muller John D. Lewis Peter M. Siegel
author_facet	Elaine Ngan Konstantin Stoletov Harvey W. Smith Jessica Common William J. Muller John D. Lewis Peter M. Siegel
author_sort	Elaine Ngan
title	LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
title_short	LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
title_full	LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
title_fullStr	LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
title_full_unstemmed	LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
title_sort	lpp is a src substrate required for invadopodia formation and efficient breast cancer lung metastasis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/7ea97a33e3164d48a89da3953228c9fb
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LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis

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