Rituximab therapy reduces organ-specific T cell responses and ameliorates experimental autoimmune encephalomyelitis.

Rituximab therapy reduces organ-specific T cell responses and ameliorates experimental autoimmune encephalomyelitis.

Recent clinical trials have established B cell depletion by the anti-CD20 chimeric antibody Rituximab as a beneficial therapy for patients with relapsing-remitting multiple sclerosis (MS). The impact of Rituximab on T cell responses remains largely unexplored. In the experimental autoimmune encephal...

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Main Authors: Nancy L Monson, Petra Cravens, Rehana Hussain, Christopher T Harp, Matthew Cummings, Maria de Pilar Martin, Li-Hong Ben, Julie Do, Jeri-Anne Lyons, Amy Lovette-Racke, Anne H Cross, Michael K Racke, Olaf Stüve, Mark Shlomchik, Todd N Eagar
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2011
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/7eb457a109ad42ca8f3e5a28c0d1260d
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https://doaj.org/article/7eb457a109ad42ca8f3e5a28c0d1260d

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