E2F function in muscle growth is necessary and sufficient for viability in Drosophila

The transcriptional regulators E2F/Dp play a critical role in cell-cycle regulation, but it is unclear why E2F-deficient flies die. Here, the authors show this is linked to the function of E2F in adult Drosophilaskeletal muscle, with the contribution of E2f1 being most important in post-fusion muscl...

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Bibliographic Details
Main Authors: Maria Paula Zappia, Maxim V. Frolov
Format: article
Language:EN
Published: Nature Portfolio 2016
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Online Access:https://doaj.org/article/7eb48b500c974934be93e3a1886a9f9a
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