E2F function in muscle growth is necessary and sufficient for viability in Drosophila

The transcriptional regulators E2F/Dp play a critical role in cell-cycle regulation, but it is unclear why E2F-deficient flies die. Here, the authors show this is linked to the function of E2F in adult Drosophilaskeletal muscle, with the contribution of E2f1 being most important in post-fusion muscl...

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Autores principales:	Maria Paula Zappia, Maxim V. Frolov
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/7eb48b500c974934be93e3a1886a9f9a
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spelling	oai:doaj.org-article:7eb48b500c974934be93e3a1886a9f9a2021-12-02T14:39:15ZE2F function in muscle growth is necessary and sufficient for viability in Drosophila10.1038/ncomms105092041-1723https://doaj.org/article/7eb48b500c974934be93e3a1886a9f9a2016-01-01T00:00:00Zhttps://doi.org/10.1038/ncomms10509https://doaj.org/toc/2041-1723The transcriptional regulators E2F/Dp play a critical role in cell-cycle regulation, but it is unclear why E2F-deficient flies die. Here, the authors show this is linked to the function of E2F in adult Drosophilaskeletal muscle, with the contribution of E2f1 being most important in post-fusion muscle.Maria Paula ZappiaMaxim V. FrolovNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Maria Paula Zappia Maxim V. Frolov E2F function in muscle growth is necessary and sufficient for viability in Drosophila
description	The transcriptional regulators E2F/Dp play a critical role in cell-cycle regulation, but it is unclear why E2F-deficient flies die. Here, the authors show this is linked to the function of E2F in adult Drosophilaskeletal muscle, with the contribution of E2f1 being most important in post-fusion muscle.
format	article
author	Maria Paula Zappia Maxim V. Frolov
author_facet	Maria Paula Zappia Maxim V. Frolov
author_sort	Maria Paula Zappia
title	E2F function in muscle growth is necessary and sufficient for viability in Drosophila
title_short	E2F function in muscle growth is necessary and sufficient for viability in Drosophila
title_full	E2F function in muscle growth is necessary and sufficient for viability in Drosophila
title_fullStr	E2F function in muscle growth is necessary and sufficient for viability in Drosophila
title_full_unstemmed	E2F function in muscle growth is necessary and sufficient for viability in Drosophila
title_sort	e2f function in muscle growth is necessary and sufficient for viability in drosophila
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/7eb48b500c974934be93e3a1886a9f9a
work_keys_str_mv	AT mariapaulazappia e2ffunctioninmusclegrowthisnecessaryandsufficientforviabilityindrosophila AT maximvfrolov e2ffunctioninmusclegrowthisnecessaryandsufficientforviabilityindrosophila
_version_	1718390664787394560

E2F function in muscle growth is necessary and sufficient for viability in Drosophila

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