TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

The elucidation of the mechanisms whereby the liver maintains glucose homeostasis is crucial for the understanding of physiological and pathological states. Here, we show a novel role of hepatic transcriptional co-activator with PDZ-binding motif (TAZ) in the inhibition of glucocorticoid receptor (G...

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Autores principales: Simiao Xu, Yangyang Liu, Ruixiang Hu, Min Wang, Oliver Stöhr, Yibo Xiong, Liang Chen, Hong Kang, Lingyun Zheng, Songjie Cai, Li He, Cunchuan Wang, Kyle D Copps, Morris F White, Ji Miao
Formato: article
Lenguaje:EN
Publicado: eLife Sciences Publications Ltd 2021
Materias:
hippo pathway effector
transcriptional co-activator with PDZ-binding motif
hepatic gluconeogenesis
glucocorticoid receptor
fasting and feeding
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d
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https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d

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