TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
The elucidation of the mechanisms whereby the liver maintains glucose homeostasis is crucial for the understanding of physiological and pathological states. Here, we show a novel role of hepatic transcriptional co-activator with PDZ-binding motif (TAZ) in the inhibition of glucocorticoid receptor (G...
Saved in:
Main Authors: | Simiao Xu, Yangyang Liu, Ruixiang Hu, Min Wang, Oliver Stöhr, Yibo Xiong, Liang Chen, Hong Kang, Lingyun Zheng, Songjie Cai, Li He, Cunchuan Wang, Kyle D Copps, Morris F White, Ji Miao |
---|---|
Format: | article |
Language: | EN |
Published: |
eLife Sciences Publications Ltd
2021
|
Subjects: | |
Online Access: | https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Modulation by Ozone of Glucocorticoid-Regulating Factors in the Lungs in Relation to Stress Axis Reactivity
by: Jith Thomas, et al.
Published: (2021) -
YSIRK-G/S-directed translocation is required for Streptococcus suis to deliver diverse cell wall anchoring effectors contributing to bacterial pathogenicity
by: Qiankun Bai, et al.
Published: (2020) -
Mechanisms of transcriptional control of glucose metabolism in hepatocytes
by: Konstantin Y. Kulebyakin, et al.
Published: (2016) -
Peptide Targeting of PDZ-Dependent Interactions as Pharmacological Intervention in Immune-Related Diseases
by: Luis H. Gutiérrez-González, et al.
Published: (2021) -
PDZ-Containing Proteins Targeted by the ACE2 Receptor
by: Célia Caillet-Saguy, et al.
Published: (2021)