TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
The elucidation of the mechanisms whereby the liver maintains glucose homeostasis is crucial for the understanding of physiological and pathological states. Here, we show a novel role of hepatic transcriptional co-activator with PDZ-binding motif (TAZ) in the inhibition of glucocorticoid receptor (G...
Enregistré dans:
Auteurs principaux: | Simiao Xu, Yangyang Liu, Ruixiang Hu, Min Wang, Oliver Stöhr, Yibo Xiong, Liang Chen, Hong Kang, Lingyun Zheng, Songjie Cai, Li He, Cunchuan Wang, Kyle D Copps, Morris F White, Ji Miao |
---|---|
Format: | article |
Langue: | EN |
Publié: |
eLife Sciences Publications Ltd
2021
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Modulation by Ozone of Glucocorticoid-Regulating Factors in the Lungs in Relation to Stress Axis Reactivity
par: Jith Thomas, et autres
Publié: (2021) -
YSIRK-G/S-directed translocation is required for Streptococcus suis to deliver diverse cell wall anchoring effectors contributing to bacterial pathogenicity
par: Qiankun Bai, et autres
Publié: (2020) -
Mechanisms of transcriptional control of glucose metabolism in hepatocytes
par: Konstantin Y. Kulebyakin, et autres
Publié: (2016) -
Peptide Targeting of PDZ-Dependent Interactions as Pharmacological Intervention in Immune-Related Diseases
par: Luis H. Gutiérrez-González, et autres
Publié: (2021) -
PDZ-Containing Proteins Targeted by the ACE2 Receptor
par: Célia Caillet-Saguy, et autres
Publié: (2021)