TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

The elucidation of the mechanisms whereby the liver maintains glucose homeostasis is crucial for the understanding of physiological and pathological states. Here, we show a novel role of hepatic transcriptional co-activator with PDZ-binding motif (TAZ) in the inhibition of glucocorticoid receptor (G...

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Bibliographic Details
Main Authors: Simiao Xu, Yangyang Liu, Ruixiang Hu, Min Wang, Oliver Stöhr, Yibo Xiong, Liang Chen, Hong Kang, Lingyun Zheng, Songjie Cai, Li He, Cunchuan Wang, Kyle D Copps, Morris F White, Ji Miao
Format: article
Language:EN
Published: eLife Sciences Publications Ltd 2021
Subjects:
hippo pathway effector
transcriptional co-activator with PDZ-binding motif
hepatic gluconeogenesis
glucocorticoid receptor
fasting and feeding
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Online Access:https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d
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https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d

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