TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states

The elucidation of the mechanisms whereby the liver maintains glucose homeostasis is crucial for the understanding of physiological and pathological states. Here, we show a novel role of hepatic transcriptional co-activator with PDZ-binding motif (TAZ) in the inhibition of glucocorticoid receptor (G...

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Détails bibliographiques
Auteurs principaux: Simiao Xu, Yangyang Liu, Ruixiang Hu, Min Wang, Oliver Stöhr, Yibo Xiong, Liang Chen, Hong Kang, Lingyun Zheng, Songjie Cai, Li He, Cunchuan Wang, Kyle D Copps, Morris F White, Ji Miao
Format: article
Langue:EN
Publié: eLife Sciences Publications Ltd 2021
Sujets:
hippo pathway effector
transcriptional co-activator with PDZ-binding motif
hepatic gluconeogenesis
glucocorticoid receptor
fasting and feeding
Medicine
R
Science
Q
Biology (General)
QH301-705.5
Accès en ligne:https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d
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https://doaj.org/article/7eb4adb4d92c49ffb5a35b4e5dddc79d

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